Generating tissues by designing the cell’s environment

Posted by Erasmus MC/TU Delft 213 days ago

We are looking for two self-motivated postdocs with a strong interest in working in a flagship multidisciplinary project between Erasmus MC and TU Delft on the topic of tissue generation, supported by the Convergence initiative. This project joins expertise in regenerative medicine (Erasmus MC) and quantitative biophysics (TU Delft) towards the aim of generating tissue-mimetic hydrogels for human disease models and tissue regeneration. Being able to precisely engineer the cell’s micro-environment holds the key for generating accurate in vitro disease models and de novo tissues. In this project, you will mimic design principles of tissues to precision-engineer the micro-environment of stem cells and direct them towards a desired tissue fate. The Delft group will focus on making and characterizing tissue-mimetic gels and studying cell-gel mechanobiology; The Erasmus MC group will focus on stem cell differentiation, cartilage repair, and an osteoarthritis-in-a-dish model. In collaboration with neighboring groups, we will also explore applications for neuronal and liver tissue.

Qualifications and skills of both postdocs:

  • PhD in a related topic such as Tissue Engineering, Physics (Biophysics or Applied Physics), (Bio)mechanical Engineering, Materials Science, Cell Biology or Biomedical Sciences
  • Ample experience in relevant experimental techniques of Mechanobiology, Cell Biology and/or Bioengineering. Experience with hydrogels, stem cells and/or cartilage is a plus
  • Proven capacity to perform research of high quality in a multidisciplinary environment

Expectations 

The postdocs should have a deep interest in the convergence of health sciences, physical sciences, and engineering to foster individual health and keep the healthcare system sustainable. They will work closely with the supervisors, Principal investigators and Collaborating investigators of the project to conduct high calibre research. They are also encouraged to initiate and lead collaborative work with other postdocs within the Convergence for health(care) initiative. Salary will be commensurate with qualification and experience.

About this position

Recruitment takes place until the vacancy is filled.
Hours a week: 36

Contact information:

Prof. Gerjo van Osch
Erasmus MC
g.vanosch@erasmusmc.nl
Prof. Gijsje Koenderink
TU-Delft
g.h.koenderink@tudelft.nl

Interested?

Generating tissues by designing the cell’s environment